I've houseruled that people's egos (and cortical stacks) carry a copy of their original DNA, if they have such a thing. For example a human born naturally on old Earth, before the Fall in a world we might recognize (pre singularity) who then uploaded later, would someday be able to grow a morph that is a clone of their original body, and have children using that body who would themselves be natural biological children similar to the parent. If they wanted to.

my personal stance on the reproduction in EP is such: -in PC locations, all children are born from exowombs in clinics. Couples that want a child get a license after long interviews (generally down in simulspaces with forks of the parents) and background checks. When adoption is granted, the child's memories are edited so he or she will only remember spending time with his or her new parents. When the kid reach maturity, he and the parents get the chance to have their memories edited again or keep the memories (inspiration: Terra-E) -on Scum barges, kids are born naturally and raised mostly by the parents, but also on a communal fashion -kinda paradoxal when most scum are individualist, but it's a good way to earn easy rep and pass useful skills and spread some memes- and when the kids reach a certain age, they leave the barge for another (inspiration: the Quarians from Mass Effect verse) -Brinkers pretty much do things as they like, and that can vary in a great many ways, from cloning to old fashioned way

I really like how Quincey has gone about it. However it's a major topic really that I would love to explained in depth in future supplement, or at least various ways of handling new morphs and egos - and how different factions might go about it.

/Incoming non-canon response :) In my version of the EP-a-verse (let me pre-stamp this with a big fat YMMV) some biomorphs are breedable (by early 21st century standards) and others are created by or require the dedicated use of sci-fi technology. So for me: Exalts, Splicers, Rusters, Bouncers & Flats (and other unlisted morphs I may include later) are able to generate offspring in an antiquated manner (in the back seat of a mini cooper at the space-prom). Only flats receive no in utero tampering/modifications however. Most transhumans get fiddled with at leeeast a little bit. Meanwhile: Ghosts, Slyphs, Neotenics, Furies, Remades, etc emerge from their creation process ready to accept an ego transfer and don't really have a nascent, or adolescent stage (neotenics don't count since they just stay 10 forever..or whatever the pre-programed age is). You won't be seeing a pimply Ghost bio-morph pining for the Slyph cheerleader in his VR simulspace class. Also, while Uplifts are able to be young, they almost all have locked genetics so they get lumped into this category of non-breeders...damn the hypercorps! In the future of my version of EP, the more bizzarre biomorphs could likely become breedable which would put transhumanity closer to posthuman (100% free breeding Uplift societies, etc). In my view, pushing the fringe biomorph clades into self-sustaining replication is one potential outcome of the scientific community's reaction to the near extinction of the Fall. Whether this will come from the more controlled hypercorps or the avant garde autonomous collectives or some combination...I haven't figured that one out yet. /end of Herbo's custom interpretation nonsense