First of all that is pretty awesome. I really like the Armitage Files/Dracula Dossier approach to campaign creation. Also the sandbox nature of that style of campaign really lends itself well to the scattershot/kitchen sink feel that I personally like in campagins. And substantiating your PCs years after the Fall- and giving them all personal connections to the TITAN program- is pretty great as well. In terms of mixing- there is a AGI "bloodline" (I cannot recall the term they use as i don't have the book in front of me right now-codeline maybe) in Transhuman called Reminbi which is kind of where I got the idea of the interlligent monetary system described above. He's an emergent AGI with predictive powers himself who I think predicted the Fall. It could be that Renminbi is a wild card that makes it difficult for Lelantos and those witht the butterfly strain to read chaotic systems in some fashion- maybe Lelnantos uses this ability to make predicitions himself and the prescecne of Renminbi creates something of a blindspot. Or it could be that renminbi is a legit xthreat (as is Lelantos) but what he is trying to achieve is counter to what Lelantos is trying to achieve. So while they are both a danger in this area at least the interests of transhumanity and the TITAN intersect. When renminbi is stopped then Lelantos can become a different type of threat as at that point the PCs would become the new blindspot as their own ability to percieve patterns in chaotic systems grows and could potentially rival his own one day (which leads to the interesting question- could these be heading into psi-epsilon territory? Could the horror at the end of the campagin be that the PCs themselves may turn into the x-threat?) Is the delta fork in your story an agent of Lelantos? Is Lelantos trying to get the PCs to find him for some reason and doing it indirectly? Or has the delta gone rogue?