Here is a all-too-plausible sketch of what biohacking can do in the future:
http://www.theatlantic.com/magazine/archive/2012/11/hacking-the-presiden...
I expect this kind of shenanigans to have become fairly common in the chaotic decades before the Fall. Genetic security was increasingly important, with world leaders worried about all sorts of hack attacks.
Interestingly, the risk abated around 20 BF or so, thanks to advances in medichines (hackproofing bodies was likely a big impetus for the research) and the possibility of resleeving made it easier to escape a biohack. So the Wall Street Plague and the MSS MS are well into the past... or so they say. Clever PCs and villains can surely find a way.
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